Understanding Triamcinolone Acetonide
Triamcinolone Acetonide is a medicine used to reduce skin irritation such as eczema, psoriasis, inflammation and rash.
This cream is available in two forms: oral and external. For external use, Triamcinolone comes in cream, ointment, lotion, liquid and aerosol.
Triamcinolone Description
The topical corticosteroids is belongs to a class of synthetic steroids utilized as inflammation suppressive and anti skin irritation agents.
The steroids in this group includeTriamcinolone Acetonide. It is formulated chemically as
21- tetrahydroxypregna-1, 9-Fluoro-11ß,16a,17,4-diene-3,6,17-acetal with acetone, 20-dione cyclic 1.
Synonyms include: 4-pregnadiene, Tramacin; 3,20- dione, Triam, Vetalog; isopropylidenedioxy- 1,,; hydroxyprednisolone acetonide ,Tricinolon
Chemical Abstracts Service Registry No: 76-25-5
OSHA IMIS Code No.T360
Chemical / Physical Properties: odorless white crystalline powder
molecular weight: 434.5
solubility in water (g/L): partly miscible
melting range: 292-294°C
molecular formula: C24H31FO6
Pharmacology usuage-
Triamcinolone and its parts are processed glucocorticoids used for their inflammation suppressive properties.
Mechanism Of Action:
The antiinflammatory impacts of corticosteroids include through inhibition of arachidonic acid, phospholipase A2 inhibitory proteins, lipocortins which control the
biosynthesis of leukotrienesand prostaglandins . The immune system is controlled by corticosteroids
because of a drop in immunoglobulin and complement concentrations, lymphocytopenia precipitation, an impairment in the working of the lymphatic system and disruption of binding of antibody-antigen.
There is concern that triamcinolone Acetonide has steroid effects which last for days.
- uneven heartbeats
- blurred vision
- sleep problems (insomnia)
- mood changes
- feeling tired
- weight gain
- puffiness in your face
- thinning of your skin
- skin itching, redness
- blistering skin
breathing difficulty, swelling of face, tongue, throat or lips.
You should not use triamcinolone acetonide for the following reasons though not exhaustive-
Previously have triamcinolone acetonide allegy.
Suffer from certain medical conditions, including stomach ulcers, diabetes, immune system disorders, skin infections,
problems with circulation.
Partaking drugs that weaken the immune system, chemotherapy medications.
Are pregnant and/or breastfeeding, as triamcinolone acetonide can damage the fetus or infant.